Broke, job hopping, indie musician, Izzy has just discovered that her ex-boyfriend- her soulmate!- got engaged to her ex-best friend, and their party happens to be tonight. Enraged and desperate, Izzy embarks on a quest to charge across Los Angeles and break that up in order to fulfill what she believes to be her destiny - before it's too late.

For Harry Fluder, life was working out exactly how he thought it was supposed to. He had a great job, loyal friends, and the perfect fiancee. However, finding one of his maybe not-so-loyal friends doing a "great job" with his perfect fiancee, was not part of the plan. After cancelling the wedding, Harry, in a drunken stupor, ponders how everything that was so right could have gone so wrong, meanwhile Bowie, Harry's best man, gets a flash of inspiration. Instead of also cancelling the amazing tropical honeymoon, why don't the two of them go instead, on an epic "homie-moon." What is supposed to be a refreshing weekend of rest and relaxation turns into an all-out bonkers adventure of epic proportions. Harry and Bowie will have the time of their lives, if they can just survive this Random Tropical Paradise.